| Date | Home | Away | Result |
|---|---|---|---|
| 9/23/25 10:00 AM | Cagliari Calcio | Frosinone Calcio | 4-1 |
| 9/23/25 11:30 AM | Udinese Calcio | Palermo FC | 2-1 |
| 9/23/25 2:00 PM | AC Milan | US Lecce | 3-0 |
| 9/24/25 10:00 AM | Parma Calcio 1913 | Spezia Calcio | 6-5a.PSO |
| 9/24/25 11:30 AM | Hellas Verona | FC Venice | 4-5a.PSO |
| 9/24/25 2:00 PM | Como Calcio | Sassuolo Calcio | 3-0 |
| 9/25/25 11:30 AM | Genoa CFC | FC Empoli | 3-1 |
| 9/25/25 2:00 PM | FC Turin | Pisa Sporting Club | 1-0 |